对健康的育龄期妇女使用储库型GnRH激动剂对AMH水平的影响

AMH is an important hormone involved in the ovarian paracrine regulation as well as a biomarker of ovarian reserve. There shows a stable AMH level during menstrual cycle, which suggest gonadotropin independence. It is well acknowledged that GnRH agonist has a down-regulation effect on H-P-O axis, but its contribution to paracrine and the mechanism are still unclear. This paper may help readers to solve this mystery to some extent.

AMH是参与卵巢旁分泌调节的一个重要激素，也是卵巢储备功能的一个生物标志物。在月经周期中AMH水平保持平稳，这表明促性腺激素具有独立性。众所周知，GnRH激动剂对H-P-O轴具有下调作用，但对旁分泌的促进作用及其机制尚不清楚。这篇论文在一定程度上或可帮助读者解开这个谜团。